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KMID : 1022820160070010018
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Journal of Multiple Sclerosis and Neuroimmunology
2016 Volume.7 No. 1 p.18 ~ p.20
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Progressive Cerebellar Atropy in a Patient with Neuromyelitis Optica Spectrum Disorder
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Shin Jong-Hwa
Seok Jin-Myoung
Cho Eun-Bin
Lee Hye-Lim
Cho Hye-Jin
Min Ju-Hong
Kim Byoong-Joon
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Abstract
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Neuromyelitis optica (NMO) is an inflammatory, demyelinating disease of the central nervous system characterized by attacks of optic neuritis and myelitis and the presence of antiaquaporin-4 antibody (anti-AQP4).There is paucity of data on patterns of brain or cerebellar atrophy in NMO, although previous studies revealed significant brain atrophy in multiple sclerosis. We report a patient with anti-AQP4 positive NMO spectrum disorder, who presented with generalized limb ataxia and gait disturbance and showed progressive cerebellar atrophy in serial follow-up brain magnetic resonance imagings.
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KEYWORD
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Neuromyelitis optica, Neuromyelitis optica spectrum disorder, Cerebellar atrophy
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